2-Hydroxypropyl-β-Cyclodextrin CAS 128446-35-5
Directory Guidance on 2-Hydroxypropyl-β-Cyclodextrin
Name: 2-Hydroxypropyl-β-Cyclodextrin
Cas: 128446-35-5
Purity: 99%min
MOQ: 1KG
Basic Info:
CAS No: | 128446-35-5 |
Formula: | C63H112O42 |
EINECS: | 420-920-1 |
Stock Availability | In stock |
Brand Name | Zhishang chemical |
Origin | China |
Chemical Structure
Product Introduction:
Cyclodextrins are molecules composed of a cyclic oligosaccharide bound to six hydroxyl groups and one carboxyl group, which can be found in many foods, like cornstarch or agar. It is also known as CYCL.
2-Hydroxypropyl-β-cyclodextrin (HBC) is a widely used modified cyclodextrin with a lipophilic cavity formed by 7 glucose units, and is used in the pharmaceutical industry and food industry, etc. Usually soluble in water , it is insoluble in most organic solvents. It has been used as a water-soluble polymer for drug delivery, polysaccharide encapsulation, and molecular recognition in molecular recognition technology.
2-Hydroxypropyl-beta-cyclodextrin has been approved by the US Food and Drug Administration (FDA) for use in food products since 1966.
It has also recently been proposed as an environmentally friendly and sustainable solvent for the production of polyethylene terephthalate (PET) by the catalytic reduction of terephthalic acid (TPA) with ethylene glycol dimethylether. 2-Hydroxypropyl-β-cyclodextrin forms a cavity that is wider than its linear size.
Nature and Specifications:
- Appearance and properties: white to slightly yellow powder
- Melting point: 278ºC (dec.)
- Refractive index: 125 ° (C=1, H2O)
- Storage condition: room temp
- Solubility: H2O: 45 % (w/v)
- Soluble in water.
Item | Specification |
Product Name | 2-Hydroxypropyl-β-Cyclodextrin Powder |
CAS No. | 128446-35-5 |
Appearance | White crystalline powder |
Shelf Life | 2 years |
Packing | 1kg/bag,25kg/bag or as your requirements |
Packaging
Product Usage:
2-hydroxypropyl-β-cyclodextrin is a compound that has been utilized in the manufacture of different products. 2-Hydroxypropyl-BETA-cyclodextrin is one of the most extensive and also widely utilized cyclodextrin derivatives. It is mainly utilized in medicine, food and cosmetics industries.
Application in the pharmaceutical industry
In the pharmaceutical industry, hydroxypropyl-BETA-cyclodextrin is an ideal injection solubilizer and pharmaceutical excipient, which can improve the water solubility of poorly soluble drugs, increase drug stability, improve drug bioavailability, and make pharmaceutical In addition, 2-hydroxypropyl-β-cyclodextrin has a high molecular weight, so it can release the drug slowly in the stomach, reducing the toxic and side effects of the drug.
2-hydroxypropyl-β-cyclodextrin is an excellent solubilizer and pharmaceutical excipient for injection as a result of its fairly low relative surface area task and hemolytic activity and also no muscle mass inflammation.
Application in the food industry
2-hydroxypropyl-β-cyclodextrin can improve the stability as well as long-lasting effect of nutrient particles in the field of food and also flavor, can mask or remedy the bad scent and also preference of food nutrient molecules, and also can enhance the production process and product quality. It has excellent solubility in water, and can be miscible with water in any type of percentage with a substitution level of 4 and above, and also can likewise be liquified in 50% ethanol and methanol.
It is also used as a thickener in ice cream, condiments, sauces, soups, gravies and beverages such as shakes and smoothies.
As a food additive: 2-hydroxypropyl-β-cyclodextrin is used as an emulsifier and stabilizer for making foods such as ice cream and sauces. It also helps in producing whipped cream at home.
As an Antioxidant: This compound acts as a preservative to keep food from spoiling or going bad. It also has anti-inflammatory properties that help relieve pain.
Application in the cosmetic sector
2-hydroxypropyl-β-cyclodextrin is used as a stabilizer, emulsifier, antiperspirant, and so on in aesthetic raw materials, which can decrease the inflammation of natural molecules in cosmetics to skin as well as mucous membrane layer cells, enhance the stability of energetic ingredients, and prevent the volatilization of nutrients, oxidation.
2-hydroxypropyl-β-cyclodextrin is often used as an emulsifier because it allows fats to mix with water or oil without forming droplets of either substance.
2-hydroxypropyl-beta-cyclodextrin can also be found in personal care products such as conditioners, shampoos, skin creams, soaps, toothpaste, and oral care products such as toothpaste and mouthwash.
Related References:
- “Local Anesthetics: Biopharmaceuticals of Cyclodextrin Complexes” – NIH, PubMed | 2000 Dec.
- “Disease Modeling of Mucopolysaccharidosis Type IIIB Using Induced Pluripotent Stem Cells” – NIH, PubMed | 2021 Oct.
- PubChem
Product Service:
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
6. Packing pictures and loading video before loading
7. Free Sample
8. Factory audit
Our Metrics
Our factory has advanced product production lines, and stable production capacity, which can achieve the goal of quickly providing high-quality products.
Our company is equipped with first-class equipment for the product production line to ensure the product quality to the greatest extent, to ensure that the net weight of the product is accurate, the packaging is well sealed, and it can meet the needs of long-distance transportation for export.
The 2-Hydroxypropyl-β-Cyclodextrin produced by our company has stable performance and a wide range of uses, which can meet the various needs of different customers.
The product price is competitive, and it has a good reputation and market share in countries all over the world.
If you need 2-Hydroxypropyl-β-Cyclodextrin or related products, please contact our company directly. Professional production and perfect service will definitely make you satisfied.
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
- After delivery, we will send a set of scanned copies of shipping documents to customers by mail, and mail the original documents in time. After the ship leaves the port, we update the shipping schedule to the customer every week and tell the customer when to arrive at the port. If customers encounter customs clearance problems, we will actively cooperate with customers to solve them. If it is an air or express delivery customer, we will provide the customer with the tracking number in time and update the information in time.
- After the customer receives the goods, we will promptly communicate with the customer about the quality and packaging of the product. Hope to get feedback from customers.
- We will provide customers with domestic market conditions and update prices in a timely manner. If conditions permit, we will also provide customers with the demand for the product in the country where they are located to help customers occupy the market.
- If there is any product quality problem, we will solve it in time. Compensation will also be made to the customer according to the third-party test report made by the customer. At present, the compensation rate due to quality objection is less than 1%.
- For our VIP customers, we have a very big preferential policy. If there is a quality problem with the product, we will be exempted from investigation and compensation, no more than three times a year.
- For ordinary customers, we will review the information provided by the customer, and then make compensation.
- Free samples can be provided before customers place an order.
- Customers can contact our technical staff at any time if they have any professional questions they do not understand. Technicians are online 24 hours a day.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.