2-Hydroxypropyl-β-Cyclodextrin CAS 128446-35-5
Directory Guidance on 2-Hydroxypropyl-β-Cyclodextrin
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Cyclodextrins are molecules composed of a cyclic oligosaccharide bound to six hydroxyl groups and one carboxyl group, which can be found in many foods, like cornstarch or agar. It is also known as CYCL.
2-Hydroxypropyl-β-cyclodextrin (HBC) is a widely used modified cyclodextrin with a lipophilic cavity formed by 7 glucose units, and is used in the pharmaceutical industry and food industry, etc. Usually soluble in water , it is insoluble in most organic solvents. It has been used as a water-soluble polymer for drug delivery, polysaccharide encapsulation, and molecular recognition in molecular recognition technology.
2-Hydroxypropyl-beta-cyclodextrin has been approved by the US Food and Drug Administration (FDA) for use in food products since 1966.
It has also recently been proposed as an environmentally friendly and sustainable solvent for the production of polyethylene terephthalate (PET) by the catalytic reduction of terephthalic acid (TPA) with ethylene glycol dimethylether. 2-Hydroxypropyl-β-cyclodextrin forms a cavity that is wider than its linear size.
Nature and Specifications:
- Appearance and properties: white to slightly yellow powder
- Melting point: 278ºC (dec.)
- Refractive index: 125 ° (C=1, H2O)
- Storage condition: room temp
- Solubility: H2O: 45 % (w/v)
- Soluble in water.
2-hydroxypropyl-β-cyclodextrin is a compound that has been utilized in the manufacture of different products. 2-Hydroxypropyl-BETA-cyclodextrin is one of the most extensive and also widely utilized cyclodextrin derivatives. It is mainly utilized in medicine, food and cosmetics industries.
Application in the pharmaceutical industry
In the pharmaceutical industry, hydroxypropyl-BETA-cyclodextrin is an ideal injection solubilizer and pharmaceutical excipient, which can improve the water solubility of poorly soluble drugs, increase drug stability, improve drug bioavailability, and make pharmaceutical In addition, 2-hydroxypropyl-β-cyclodextrin has a high molecular weight, so it can release the drug slowly in the stomach, reducing the toxic and side effects of the drug.
2-hydroxypropyl-β-cyclodextrin is an excellent solubilizer and pharmaceutical excipient for injection as a result of its fairly low relative surface area task and hemolytic activity and also no muscle mass inflammation.
Application in the food industry
2-hydroxypropyl-β-cyclodextrin can improve the stability as well as long-lasting effect of nutrient particles in the field of food and also flavor, can mask or remedy the bad scent and also preference of food nutrient molecules, and also can enhance the production process and product quality. It has excellent solubility in water, and can be miscible with water in any type of percentage with a substitution level of 4 and above, and also can likewise be liquified in 50% ethanol and methanol.
It is also used as a thickener in ice cream, condiments, sauces, soups, gravies and beverages such as shakes and smoothies.
As a food additive: 2-hydroxypropyl-β-cyclodextrin is used as an emulsifier and stabilizer for making foods such as ice cream and sauces. It also helps in producing whipped cream at home.
As an Antioxidant: This compound acts as a preservative to keep food from spoiling or going bad. It also has anti-inflammatory properties that help relieve pain.
Application in the cosmetic sector
2-hydroxypropyl-β-cyclodextrin is used as a stabilizer, emulsifier, antiperspirant, and so on in aesthetic raw materials, which can decrease the inflammation of natural molecules in cosmetics to skin as well as mucous membrane layer cells, enhance the stability of energetic ingredients, and prevent the volatilization of nutrients, oxidation.
2-hydroxypropyl-β-cyclodextrin is often used as an emulsifier because it allows fats to mix with water or oil without forming droplets of either substance.
2-hydroxypropyl-beta-cyclodextrin can also be found in personal care products such as conditioners, shampoos, skin creams, soaps, toothpaste, and oral care products such as toothpaste and mouthwash.
- “Local Anesthetics: Biopharmaceuticals of Cyclodextrin Complexes” – NIH, PubMed | 2000 Dec.
- “Disease Modeling of Mucopolysaccharidosis Type IIIB Using Induced Pluripotent Stem Cells” – NIH, PubMed | 2021 Oct.
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
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7. Free Sample
8. Factory audit
Our factory has advanced product production lines, and stable production capacity, which can achieve the goal of quickly providing high-quality products.
Our company is equipped with first-class equipment for the product production line to ensure the product quality to the greatest extent, to ensure that the net weight of the product is accurate, the packaging is well sealed, and it can meet the needs of long-distance transportation for export.
The 2-Hydroxypropyl-β-Cyclodextrin produced by our company has stable performance and a wide range of uses, which can meet the various needs of different customers.
The product price is competitive, and it has a good reputation and market share in countries all over the world.
If you need 2-Hydroxypropyl-β-Cyclodextrin or related products, please contact our company directly. Professional production and perfect service will definitely make you satisfied.
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.