4-Acetamidophenol CAS 103-90-2
Directory Guidance on 4-Acetamidophenol
Name: 4-Acetamidophenol
Cas: 103-90-2
Purity:Â 99%min
MOQ: 1KG
Basic Info:
| CAS No: | 103-90-2 |
| Formula: | C8H9NO2 |
| EINECS: | 203-157-5 |
| Stock Availability | In stock |
| Brand Name | Zhishang chemical |
| Origin | China |
Chemical Structure
Product Introduction:
4-Acetamidophenol, also known as acetaminophen, chemical name is N-(4-Hydroxyphenyl)acetamide, trade name is paracetamol, it belongs to acetanilide antipyretic analgesic. Its look is white crystal or crystalline powder, odorless, a little bitter taste, easily soluble in hot water or ethanol, soluble in acetone, virtually insoluble in cold water and also oil ether.
4-Acetamidophenol is stable below 45°C, but it will be hydrolyzed into p-aminophenol if exposed to humid air, and then further oxidized, and the color will gradually become pink, brown, and finally black, so it should be stored in a cool, dry place.
Acetaminophen is a phenolic organic compound and an important pharmaceutical intermediate. Primarily utilized for high temperature caused by cold or flu, as well as likewise used to alleviate mild to moderate discomfort such as frustration, joint pain, migraine, toothache, muscle mass discomfort, neuralgia, dysmenorrhea, etc.
Nature and Specifications:
- Density: 1,293 g/cm3
- Melting point: 168-172 °C(lit.)
- Water solubility: 14 g/L (20 ºC)
- Flash point: 11 °C
- Acidity coefficient: 9.86±0.13(Predicted)
- Refractive index: 1.5810 (rough estimate)
| Item | Specification |
| Product Name | 4-Acetamidophenol Powder |
| CAS No. | 103-90-2 |
| Appearance | White crystalline powder |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Product Packaging
Product Usage:
Acetamidophenol is the most generally used non-anti-inflammatory, analgesic as well as antipyretic drug. Its antipyretic result is comparable to aspirin, yet its analgesic impact is weaker.
Medically, 4-Acetamidophenol is mainly used for high temperature, headache and also relief of moderate and light discomfort brought on by colds, such as joint pain, muscular tissue discomfort, neuralgia, migraine, dysmenorrhea, cancer discomfort and postoperative analgesia.
Additionally, it can additionally be used in the synthesis of the medication paracetamol, as an intermediate in organic synthesis, as a stabilizer for photographic chemicals and also hydrogen peroxide.
Antipyretic effect:
Acetaminophen is an antipyretic and analgesic drug, which uniquely prevents the synthesis of prostaglandins in the hypothalamic thermoregulatory center by preventing cyclooxygenase, resulting in peripheral vasodilation as well as sweating to accomplish antipyretic impact. Its antipyretic result is strong. Comparable to aspirin.
Analgesic effect:
4-Acetamidophenol plays an analgesic result by inhibiting the synthesis as well as release of prostaglandins, and so on, and increasing the pain limit. It is an outer analgesic, and also its impact is weaker than that of aspirin. Compared with aspirin, acetaminophen has the advantages of less irritation and less allergic reaction, and its antipyretic and analgesic effect is similar to that of phenacetin.
In place of other medicines:
4-Acetamidophenol can likewise be made use of in people that are sensitive, inappropriate or intolerant for pain killers: such as chickenpox, hemophilia and other bleeding disorders (consisting of those on anticoagulant treatment), as well as light peptic ulcers and also gastritis clients, and so on.
Adverse Reactions:
- Allergic reactions: 4-Acetamidophenol has fewer and milder side effects in therapeutic doses. Allergic reactions such as rash and urticaria are occasionally seen. Methemoglobinemia can occur in individual cases.
- Liver and kidney damage: Long-term use of large amounts can cause liver and kidney damage and thrombocytopenia, and even jaundice, oliguria, acute severe hepatitis, leading to coma and death. Large doses may also cause nausea, vomiting, stomach pain, stomach cramps, diarrhea, anorexia, sweating, etc.
- Due to the immature development of liver and kidney functions in children under 3 years old and the poor detoxification and excretion functions, the use of acetaminophen tablets should be avoided as much as possible. In addition, people with liver and kidney deficiency as well as expecting women must be used with caution. Lasting drug users should on a regular basis inspect blood and also liver and kidney function.
Related References:
- “Improving Acetaminophen Hepatotoxicity Study in Rat” – Springer, Link | 02 April 2022.
- “Photocatalytic Degradation of 4-Acetamidophenol in Modified Titanium Dioxide” – Springer, Link | 26 July 2013.
- “The Safe Use of Drugs Like Acetaminophen” – FDA | Excerpt: May 07, 2022.
- Wikipedia
Product Service:
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
6. Packing pictures and loading video before loading
7. Free Sample
8. Factory audit
Our Metrics
Our factory has advanced product production lines, and stable production capacity, which can achieve the goal of quickly providing high-quality products.
Our company is equipped with first-class equipment for the product production line to ensure the product quality to the greatest extent, to ensure that the net weight of the product is accurate, the packaging is well sealed, and it can meet the needs of long-distance transportation for export.
The 4-Acetamidophenol produced by our company has stable performance and a wide range of uses, which can meet the various needs of different customers.
The product price is competitive, and it has a good reputation and market share in countries all over the world.
If you need 4-Acetamidophenol/Acetaminophen or related products, please contact our company directly. Professional production and perfect service will definitely make you satisfied.
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
- After delivery, we will send a set of scanned copies of shipping documents to customers by mail, and mail the original documents in time. After the ship leaves the port, we update the shipping schedule to the customer every week and tell the customer when to arrive at the port. If customers encounter customs clearance problems, we will actively cooperate with customers to solve them. If it is an air or express delivery customer, we will provide the customer with the tracking number in time and update the information in time.
- After the customer receives the goods, we will promptly communicate with the customer about the quality and packaging of the product. Hope to get feedback from customers.
- We will provide customers with domestic market conditions and update prices in a timely manner. If conditions permit, we will also provide customers with the demand for the product in the country where they are located to help customers occupy the market.
- If there is any product quality problem, we will solve it in time. Compensation will also be made to the customer according to the third-party test report made by the customer. At present, the compensation rate due to quality objection is less than 1%.
- For our VIP customers, we have a very big preferential policy. If there is a quality problem with the product, we will be exempted from investigation and compensation, no more than three times a year.
- For ordinary customers, we will review the information provided by the customer, and then make compensation.
- Free samples can be provided before customers place an order.
- Customers can contact our technical staff at any time if they have any professional questions they do not understand. Technicians are online 24 hours a day.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
