5-Hydroxymethylfurfural CAS 67-47-0
Directory Guidance on 5-Hydroxymethylfurfural
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|Brand Name||Zhishang chemical|
5-Hydroxymethylfurfural (referred to as 5-HMF), also known as 5-hydroxymethyl-2-furfural, 5-hydroxymethyl-2-furfural, etc., molecular formula is C6H6O3, colorless needle crystal, with chamomile flowers Flavor is a small molecule compound containing a furan ring. It is one of the common ingredients in Chinese herbal medicines and Chinese medicine compounds, and is also widely found in raisins, dairy products, honey, cakes and other foods.
5-Hydroxymethylfurfural is a furfural compound with a furan ring structure produced by dehydration of monosaccharide compounds such as glucose under high temperature or weak acid conditions. At present, 5-HMF has been found in a variety of baked goods. 5-HMF, which is derived from its own sugar, is a potential “carbon neutral” fuel and chemical feedstock.
5-Hydroxymethylfurfural is an important chemical raw material. Its molecule contains an aldehyde group and a hydroxymethyl group, which can undergo hydrogenation, oxidative dehydrogenation, esterification, halogenation, polymerization, hydrolysis and other chemical reactions. It is a precursor to several compounds, including furfural and furfural.
Nature and Specifications:
- Density: 1.243 g/mL at 25 °C(lit.)
- Boiling point: 114-116 °C1 mm Hg(lit.)
- Melting point: 28-34 °C (lit.)
- Flash point: 175 °F
- Acidity coefficient: 12.82±0.10(Predicted)
- Refractive index: n20/D 1.562(lit.)
5-Hydroxymethylfurfural (5-HMF) is an important furan compound, which is widely used in medicine, chemistry, energy and other fields due to its excellent chemical properties. one of the platform chemicals.
As an important chemical raw material, 5-hydroxymethyl furfural is often used in the synthesis of many useful compounds and new polymer materials, including medicine, resin plastics, diesel fuel additives, etc.
For content determination/identification/pharmacological experiments, etc. Pharmacological and pharmacological effects: The compound can effectively prevent and treat neurodegenerative diseases, cognitive impairment and cardiovascular disease against myocardial ischemia, inhibit tumors, and lower blood cholesterol.
In addition to this, 5-Hydroxymethylfurfural is a chemical found in sugar production. It is used in the manufacturing process to produce sugar, molasses and ethanol. It has many industrial uses, but is also used in plastic production, as a pesticide and as a fungicide.
Its derivatives have great application prospects in the fields of fine chemicals, medicine, degradable plastics, etc. In particular, bio-based PEF polyester based on furandicarboxylic acid has shown advantages over petroleum-based PET (polyethylene terephthalate). of many characteristics.
5-Hydroxymethylfurfural can be used to detect metabolites of glucose bolus infusion.
The Effect of 5-Hydroxymethylfurfural:
1. Antioxidant activity
At present, there are many studies related to the antioxidant activity of 5-Hydroxymethylfurfural. Studies have found that 5-Hydroxymethylfurfural may increase the activity of the antioxidant enzyme SOD in brain tissue and reduce lipid peroxidation, thereby improving learning and memory. ability.
2. Anti-myocardial ischemia
5-Hydroxymethylfurfural can reduce the content of malondialdehyde (MDA) in myocardial tissue and lactate dehydrogenase (LDH) in serum of mice with myocardial ischemia, and has obvious antioxidant and cardiovascular protection functions. It can be used for Preparation of medicines for treating cardiovascular disease and anti-myocardial ischemia.
3. Anti-tumor cell proliferation
In 2008, it was found that 5-hydroxymethylfurfural in Rehmannia glutinosa could induce tissue hypoxia, which may be useful for cancer treatment and clinical treatment of sickle cell anemia.
4. Improve blood rheology
Studies have found that Rehmannia glutinosa extract can improve the deformability of red blood cells, inhibit red blood cell aggregation, and improve blood rheology by enhancing the activity of the fibrinolytic system, thereby presenting a blood flow promotion effect. The effect is weak, or not shown; and the content of 5-hydroxymethyl furfural in Rehmannia glutinosa is 20 times that in Rehmannia glutinosa, it is inferred that it may be the active ingredient in Rehmannia glutinosa.
5. Regulate Ca2+ balance
5-Hydroxymethylfurfural in ume plum has Ca2+ antagonism; 5-Hydroxymethylfurfural has antioxidant, anti-microtubule-related protein hyperphosphorylation, anti-β-amyloid deposition in the brain, stabilizes cell membrane, and regulates calcium ion balance. and improve the survival rate of nerve cells in pathological damage, so as to improve the anti-injury ability of Alzheimer’s disease and Parkinson’s disease cell models and the behavioral ability of animal models. At the same time, 5-hydroxymethylfurfural The compounds can also be used to prepare medicines and health products for the prevention and treatment of neurodegenerative diseases and cognitive impairment.
The study found that the bamboo fungus extract has the effect of anti-tyrosinase activity, and the active substance was isolated and identified as 5-hydroxymethyl furfural; further pharmacodynamic studies showed that 5-hydroxymethyl furfural was an oxidized levoraldehyde Noncompetitive inhibitor of dopa.
7. Affects glycyrrhizic acid metabolism
Oral administration of honey containing glucose, sucrose, 5-hydroxymethylfurfural and other ingredients to rabbits, and observation of the metabolism of glycyrrhizic acid and glycyrrhetinic acid in rabbits, found that 5-hydroxymethylfurfural has an enhanced di- It has anti-inflammatory, anti-tumor and lowering blood cholesterol effects, which is achieved by inhibiting the oxidation of glycyrrhetic acid and increasing the absorption of glycyrrhetic acid in the body.
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
6. Packing pictures and loading video before loading
7. Free Sample
8. Factory audit
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Our company is equipped with first-class equipment for the product production line to ensure the product quality to the greatest extent, to ensure that the net weight of the product is accurate, the packaging is well sealed, and it can meet the needs of long-distance transportation for export.
The 5-Hydroxymethylfurfural produced by our company has stable performance and a wide range of uses, which can meet the various needs of different customers.
The product price is competitive, and it has a good reputation and market share in countries all over the world.
If you need 5-Hydroxymethylfurfural or related products, please contact our company directly. Professional production and perfect service will definitely make you satisfied.
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