Benzocaine CAS 94-09-7
Directory Guidance on Benzocaine
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Benzocaine, also known as ethyl p-aminobenzoate, is a white needle-like crystal. Melting point is 90-92 ℃, slightly soluble in water and easily soluble in natural solvents. Such as: ethanol, chloroform, ether, soluble in almond oil, olive oil.
It is a type of medicine with solid fat solubility, so it is easy to incorporate with the lipid layer of mucous membrane layer or skin, but it is hard to pass through right into the human body to create poisoning.
As a water-insoluble anesthetic, benzocaine has analgesic and antipruritic results. It is scientifically made use of for wound anesthetic, abscess surface anesthesia, mucosal surface anesthesia and also pile anesthetic. Its medicinal impact is generally to obstruct nerve endings to ease Pain as well as itchiness.
The anesthetic effect of benzocaine is weak than that of procaine, it can not be utilized for infiltration, and also the local absorption is slow as well as sturdy. It is hydrolyzed to p-aminobenzoic acid, which is non-irritating as well as poisonous when the normal focus is 2% to 10%.
Its poisoning is only comparable to 5% or 10% of drug, and also the maximum safe amount for topical usage is 5g or 25mL of 20% option. Inhibits the transmission of nerve impulses from sensory nerve endings, dulls the taste, and has a framework similar to procaine, so it is taken in gradually as well as has a lasting anesthetic effect.
Nature and Specifications:
- Density: 1.17
- Boiling point: 172 °C (12.7517 mmHg)
- Melting point: 88-90 °C
- Flash point: 172°C/13mm
- Refractive index: 1.5502
- Solubility: alcohol: soluble1 gm in 5 ml
- Acidity coefficient (pKa): 2.5(at 25℃)
Benzocaine, as a water-insoluble anesthetic, has analgesic and also antipruritic impacts. As a result, it is frequently made use of as an anesthetic or painkiller. use:
Used as an anesthetic:
Mostly utilized for wound surface area, ulcer surface, mucosa surface area as well as hemorrhoids anesthesia pain and also irritation, its lotion can additionally be utilized as nasopharyngeal catheter, endoscopic as well as other lubrication and discomfort alleviation.
Benzocaine is a water-insoluble local anesthetic utilized as a topical applicator for post-operative trauma pain alleviation and also ulcer discomfort.
Benzocaine products are made use of as anesthetics for the skin and mucous membrane layers. The result is defined by fast onset of activity, analgesic result can be created in concerning 30 secs, and no permeability to mucous membranes, reduced toxicity, and also will not influence the cardio system as well as nervous system.
Benzocaine is a fat-soluble surface anesthetic. Compared with a number of other local anesthetics, such as lidocaine and also dicaine, its action strength is tiny, therefore, when it acts on the mucous membrane, it will not make people feel uncomfortable due to anesthesia.
Safety representatives for shielding from the sun:
UV absorber can be utilized, generally utilized in sunscreen and also tanning cosmetics, chemically steady to light as well as air, and safe to skin. It likewise has the capability to create a movie on the skin, and also can likewise be made use of as an intermediate for other UV absorbers.
Various other usages:
Benzocaine can be utilized as precursor basic materials such as oxoform, oxocaine and procaine.
Short-term alleviation for unpleasant as well as itchy skin discomfort, small burns, sunburns, injuries as well as insect bites. Auricular preparations are utilized to alleviate pain as well as itching in severe congestive, congestive otitis externa, swimmer’s otitis and also exterior usage.
It is also reliable for tooth pain, aching throat, mouth abscess, various piles, rectal fissures, genital itchiness, and also as a male genital desensitizer to reduce climaxing. Or as an anesthetic lube for catheters and endoscopic tubes.
Advice on Taking Medicines Containing Benzocaine:
It is recommended that patients use benzocaine-containing drugs in strict accordance with the instructions. If signs and symptoms of methemoglobinemia occur during use, such as skin, lip mucosa, nail bed bruising, shortness of breath, rapid heart rate, Fatigue, confusion, headache, dizziness, etc., please seek medical attention in time. Children under the age of 2 should be used under the guidance of a physician.
It is recommended that manufacturers improve product instructions in a timely manner; increase relevant safety information; strengthen the publicity of rational drug use to ensure that product safety information is communicated to patients and doctors in a timely manner; and strengthen adverse drug reaction monitoring.
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
6. Packing pictures and loading video before loading
7. Free Sample
8. Factory audit
Our factory has advanced product production lines, and stable production capacity, which can achieve the goal of quickly providing high-quality products.
Our company is equipped with first-class equipment for the product production line to ensure the product quality to the greatest extent, to ensure that the net weight of the product is accurate, the packaging is well sealed, and it can meet the needs of long-distance transportation for export.
The benzocaine produced by our company has stable performance and a wide range of uses, which can meet the various needs of different customers.
The product price is competitive, and it has a good reputation and market share in countries all over the world.
If you need benzocaine or related products, please contact our company directly. Professional production and perfect service will definitely make you satisfied.
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.