Clindamycin Phosphate CAS 24729-96-2

Directory Guidance on Clindamycin Phosphate

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Name: Clindamycin Phosphate

Cas: 24729-96-2

Purity: 99%min

MOQ: 1KG

Basic Info:

CAS No:24729-96-2
Formula:C18H34ClN2O8PS
EINECS:246-433-0
Stock AvailabilityIn stock
Brand NameZhishang chemical
OriginChina

Chemical Structure

Clindamycin phosphate

Product Introduction:

Clindamycin phosphate, also known as Cleocinphosphate, chemical name: 6-(1-methyl-trans-1-propyl-L-2-pyrrolidinecarboxamido)-1-thio-7(S) -Chloro-6,7,8-trideoxy-L-threo-α-D-galactooctanopyranoside-2-dihydrogen phosphate. It is a chemical semi-synthetic clindamycin derivative, which rapidly hydrolyzes clindamycin in vivo to show pharmacological activity.

Clindamycin phosphate is a white or off-white crystalline powder at room temperature, odorless, bitter in taste, and hygroscopic. Soluble in water and dilute lye, slightly soluble in methanol, almost insoluble in ethanol and ether.

Product Features:

High blood concentration can be obtained immediately after administration by injection, and then it is widely distributed in tissues and body fluids, such as lung, tonsil, liver and gallbladder, peritoneal fluid, appendix, prostate and uterus and fallopian tubes. Can reach high concentrations, especially in bone and joint tissue is characterized by higher concentrations. However, the ability to penetrate the blood-cerebrospinal liquid obstacle is poor, as well as the concentration in mind tissue is reduced.

It has no anti-bacterial task in vitro, as well as can be rapidly hydrolyzed right into clindamycin after going into the body to apply its medicinal impact. Its mechanism of activity, antibacterial spectrum, signs, as well as therapeutic results coincide as those of clindamycin. Nevertheless, its fat solubility as well as permeability are much better than that of clindamycin, and also it can be carried out by mouth or intramuscularly as well as intravenously.

Compared to clindamycin, clindamycin phosphate has 4 to 8 times stronger anti-bacterial impact, good absorption, high bone cells focus, and also strong antibacterial activity against Gram-positive cocci and anaerobic microorganisms.

Its antibacterial range is:

Gram-positive cocci consist of penicillin G-resistant Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus (other than Streptococcus phosphate), Streptococcus pneumoniae, Micrococcus, etc.

Gram-positive bacilli consist of Clostridium, Diphtheria, and the like.

Anaerobic microorganisms include Clostridium, Bacteroides, Clostridium, Propionibacterium, Eubacterium, anaerobic cocci and so forth.

Nature and Specifications:

Product Packaging

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Product Usage:

Used in the manufacture of medicines to deal with inflammation

Clinically, clindamycin phosphate is mainly made use of to deal with tonsillitis, suppurative otitis media, sinus problems, severe bronchitis, severe worsening of chronic respiratory disease, pneumonia, lung abscess, bronchiectasis challenging infection and skin and soft tissue infection.

Such as furuncle, carbuncle, abscess, cellulitis, injury infection, shed infection, postoperative infection, etc. And urinary tract acute urethritis, acute pyelonephritis, prostatitis and so on. Also used for osteomyelitis, sepsis, peritonitis, oral infections, etc.

Clindamycin phosphate enters the body and acts, mainly metabolized in the liver, excreted in bile and feces, and partially excreted in urine.

used as an antibiotic

Clindamycin phosphate is a broad-spectrum antibiotic with both anti-anaerobic and aerobic effects. With the exception of Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus viridans as well as a lot of Staphylococcus aureus methicillin-resistant pressures, a lot of anaerobic germs are effective.

It is scientifically used for abdominal and also pelvic infections caused by anaerobic germs including Bacteroides fragilis, Clostridium perfringens, Actinomyces, and so on, as well as respiratory system system, joint as well as soft tissue, bone cells caused by delicate Gram-positive bacteria. biliary system infection and also sepsis, endocarditis and more.

Compared with clindamycin, its effect has the features of high anti-bacterial task, rapid absorption, solid lipid solubility and leaks in the structure, and much less side effects. It is extensively distributed in the body as well as has high tissue concentration, especially in bone tissue. It has solid antibacterial result on all sort of Gram-positive germs and also has few side effects.

Related References:

Product Service:

1. Certificate Of Analysis (COA)

2. Material Safety Data Sheet (MSDS)

3. Route of synthesis (ROS)

4. Method of Aanlysis (MOA)

5. Nuclear Magnetic Resonance (NMR)

6. Packing pictures and loading video before loading

7. Free Sample

8. Factory audit

Our Metrics

Our factory has advanced product production lines, and stable production capacity, which can achieve the goal of quickly providing high-quality products.

Our company is equipped with first-class equipment for the product production line to ensure the product quality to the greatest extent, to ensure that the net weight of the product is accurate, the packaging is well sealed, and it can meet the needs of long-distance transportation for export.

The clindamycin phosphate produced by our company has stable performance and a wide range of uses, which can meet the various needs of different customers.

The product price is competitive, and it has a good reputation and market share in countries all over the world.

If you need clindamycin phosphate or related products, please contact our company directly. Professional production and perfect service will definitely make you satisfied.

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