Clindamycin Phosphate CAS 24729-96-2
Name: Clindamycin Phosphate
Cas: 24729-96-2
Purity:Â 99%min
MOQ: 1KG
Basic Info:
| CAS No: | 24729-96-2 |
| Formula: | C18H34ClN2O8PS |
| EINECS: | 246-433-0 |
| Stock Availability | In stock |
| Brand Name | Zhishang chemical |
| Origin | China |
Chemical Structure
Product Introduction:
Clindamycin phosphate, also known as Cleocinphosphate, chemical name: 6-(1-methyl-trans-1-propyl-L-2-pyrrolidinecarboxamido)-1-thio-7(S) -Chloro-6,7,8-trideoxy-L-threo-α-D-galactooctanopyranoside-2-dihydrogen phosphate. It is a chemical semi-synthetic clindamycin derivative, which rapidly hydrolyzes clindamycin in vivo to show pharmacological activity.
Clindamycin phosphate is a white or off-white crystalline powder at room temperature, odorless, bitter in taste, and hygroscopic. Soluble in water and dilute lye, slightly soluble in methanol, almost insoluble in ethanol and ether.
Product Features:
High blood concentration can be obtained immediately after administration by injection, and then it is widely distributed in tissues and body fluids, such as lung, tonsil, liver and gallbladder, peritoneal fluid, appendix, prostate and uterus and fallopian tubes. Can reach high concentrations, especially in bone and joint tissue is characterized by higher concentrations. However, the ability to penetrate the blood-cerebrospinal liquid obstacle is poor, as well as the concentration in mind tissue is reduced.
It has no anti-bacterial task in vitro, as well as can be rapidly hydrolyzed right into clindamycin after going into the body to apply its medicinal impact. Its mechanism of activity, antibacterial spectrum, signs, as well as therapeutic results coincide as those of clindamycin. Nevertheless, its fat solubility as well as permeability are much better than that of clindamycin, and also it can be carried out by mouth or intramuscularly as well as intravenously.
Compared to clindamycin, clindamycin phosphate has 4 to 8 times stronger anti-bacterial impact, good absorption, high bone cells focus, and also strong antibacterial activity against Gram-positive cocci and anaerobic microorganisms.
Its antibacterial range is:
Gram-positive cocci consist of penicillin G-resistant Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus (other than Streptococcus phosphate), Streptococcus pneumoniae, Micrococcus, etc.
Gram-positive bacilli consist of Clostridium, Diphtheria, and the like.
Anaerobic microorganisms include Clostridium, Bacteroides, Clostridium, Propionibacterium, Eubacterium, anaerobic cocci and so forth.
Nature and Specifications:
- Density: 1.41 g/cm3
- Melting point: 114ºC
- Boiling point: 159°C
- Refractive index: 122 ° (C=1, H2O)
- Storage conditions: Sealed in dry, 2-8°C
- Solubility: soluble224mg/mL at 25°C
- Water solubility: Freely soluble in water
| Item | Specification |
| Product Name | Clindamycin Phosphate Powder |
| CAS No. | 24729-96-2 |
| Appearance | White crystalline powder |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Product Packaging
Product Usage:
Used in the manufacture of medicines to deal with inflammation
Clinically, clindamycin phosphate is mainly made use of to deal with tonsillitis, suppurative otitis media, sinus problems, severe bronchitis, severe worsening of chronic respiratory disease, pneumonia, lung abscess, bronchiectasis challenging infection and skin and soft tissue infection.
Such as furuncle, carbuncle, abscess, cellulitis, injury infection, shed infection, postoperative infection, etc. And urinary tract acute urethritis, acute pyelonephritis, prostatitis and so on. Also used for osteomyelitis, sepsis, peritonitis, oral infections, etc.
Clindamycin phosphate enters the body and acts, mainly metabolized in the liver, excreted in bile and feces, and partially excreted in urine.
used as an antibiotic
Clindamycin phosphate is a broad-spectrum antibiotic with both anti-anaerobic and aerobic effects. With the exception of Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus viridans as well as a lot of Staphylococcus aureus methicillin-resistant pressures, a lot of anaerobic germs are effective.
It is scientifically used for abdominal and also pelvic infections caused by anaerobic germs including Bacteroides fragilis, Clostridium perfringens, Actinomyces, and so on, as well as respiratory system system, joint as well as soft tissue, bone cells caused by delicate Gram-positive bacteria. biliary system infection and also sepsis, endocarditis and more.
Compared with clindamycin, its effect has the features of high anti-bacterial task, rapid absorption, solid lipid solubility and leaks in the structure, and much less side effects. It is extensively distributed in the body as well as has high tissue concentration, especially in bone tissue. It has solid antibacterial result on all sort of Gram-positive germs and also has few side effects.
Related References:
- “Clindamycin Phosphate Retinoic Acid Gel for Acne Treatment” – NIH, PubMed | 2019 Apr 1.
- “Effects of selected antibiotics on oxonase in vitro in human serum and in vivo in mouse serum and liver” – NIH, PubMed | 2006 Aug.
- Wikidata
Product Service:
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
6. Packing pictures and loading video before loading
7. Free Sample
8. Factory audit
Our Metrics
Our factory has advanced product production lines, and stable production capacity, which can achieve the goal of quickly providing high-quality products.
Our company is equipped with first-class equipment for the product production line to ensure the product quality to the greatest extent, to ensure that the net weight of the product is accurate, the packaging is well sealed, and it can meet the needs of long-distance transportation for export.
The clindamycin phosphate produced by our company has stable performance and a wide range of uses, which can meet the various needs of different customers.
The product price is competitive, and it has a good reputation and market share in countries all over the world.
If you need clindamycin phosphate or related products, please contact our company directly. Professional production and perfect service will definitely make you satisfied.
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
- After delivery, we will send a set of scanned copies of shipping documents to customers by mail, and mail the original documents in time. After the ship leaves the port, we update the shipping schedule to the customer every week and tell the customer when to arrive at the port. If customers encounter customs clearance problems, we will actively cooperate with customers to solve them. If it is an air or express delivery customer, we will provide the customer with the tracking number in time and update the information in time.
- After the customer receives the goods, we will promptly communicate with the customer about the quality and packaging of the product. Hope to get feedback from customers.
- We will provide customers with domestic market conditions and update prices in a timely manner. If conditions permit, we will also provide customers with the demand for the product in the country where they are located to help customers occupy the market.
- If there is any product quality problem, we will solve it in time. Compensation will also be made to the customer according to the third-party test report made by the customer. At present, the compensation rate due to quality objection is less than 1%.
- For our VIP customers, we have a very big preferential policy. If there is a quality problem with the product, we will be exempted from investigation and compensation, no more than three times a year.
- For ordinary customers, we will review the information provided by the customer, and then make compensation.
- Free samples can be provided before customers place an order.
- Customers can contact our technical staff at any time if they have any professional questions they do not understand. Technicians are online 24 hours a day.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
