Methyl 4-aminopyridine-2-carboxylate CAS 71469-93-7
Directory Guidance on Polyvinylpyrrolidone K90 (PVP K90)
Name: Methyl 4-aminopyridine-2-carboxylate
Cas: 71469-93-7
Purity: 99%min
MOQ: 1KG
Basic Info:
| CAS No: | 71469-93-7 |
| Formula: | C7H8N2O2 |
| EINECS: | – |
| Stock Availability | In stock |
| Brand Name | Zhishang chemical |
| Origin | China |
Chemical Structure
Product Introduction:
Product summary
Methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 is a compound of considerable importance in the field of organic synthesis, with a unique chemical structure that can facilitate a variety of properties and multiple applications. The molecular formula of the compound is C7H8N2O2 and the molecular weight is about 152.15. It is a pyrazine derivative with a specific functional group, and the presence of amino acids and ester groups makes it exhibit unique activity in chemical reactions.
Visually, the methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 usually appears as a white to white crystalline powder. The storage and use of this physical form is very convenient, and it is also convenient for precise determination and start-up in a variety of chemical synthesis processes. Good crystallization indicates that the compound has a more regular molecular arrangement, which affects physical properties, such as solubility and stability, to a certain extent.
Second, physical characteristics
(1) Solubility
The solubility of methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 varies with the solvent. General organic solvents such as methanol, ethanol, dichloromethane, etc., have good solubility. In methanol, due to polarity and hydrogen bonding, specific interactions can be formed with amino and esterase in raspberry, promoting dissolution.
In water, the solubility is lower. This is because although the polarity of water is high, the hydrophobic part of the coated molecule (such as the pyrazine ring, etc.) limits the dispersion of water. However, under certain specific conditions, such as adjusting the pH value of the solution or adding the appropriate nasal solvent, the solubility to water can be improved. For example, under weakly alkaline conditions, amino acids can increase their interaction with water molecules and improve solubility through a certain degree of ionization.
(2) Melting point and boiling point
The methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 generally has a melting point between 150-155 ° C. The melting point is one of the important physical properties of a compound, which reflects the intermolecular force and the stability of the crystal structure. During the heating process, when the temperature reaches the melting point, the compound changes from a solid to a liquid state, accompanied by changes in molecular arrangement and energy absorption.
Regarding boiling point, the boiling point of a compound is difficult to determine due to the possibility of decomposition and other reactions at higher temperatures. But under normal pressure, it can be inferred through some theoretical calculations and related experiments that the boiling point is higher, and requires distillation and other work under reduced pressure to separate and purify.
(3) Density and refractive index
The density of the compound is about 1.25 g/cm to the power of 3, which is the mass per unit volume of the substance and is closely related to the composition and structure of the molecule. The molecule of methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 consists of nitrogen, oxygen and other atoms. The relative mass of these atoms and the spatial arrangement of the molecules determine the density.
The refractive index of methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 is also one of the important optical properties of the substance, with a refractive index of about 1.57. Refractive index reflects the degree of refraction of light propagation in a compound, and is related to the distribution of molecular electron clouds and the characteristics of chemical bonds. By measuring the refractive index, the purity and structure of the compound can be analyzed and judged to a certain extent.
Three, chemical properties
(1) Acidity and alkalinity
The methyl 4-aminopyridin-2-carboxylate cass 71469-93-7 molecule has a specific amino acid group (-nh2). In aqueous solutions, amino groups can accommodate the proton ammonium ion (h +) form (-nh ∝). The strength of alkalinity is related to the electron cloud density of the amino group and the surrounding chemical environment. At the same time, the molecular lactone group (-COOCH) can undergo hydrolysis reaction under certain conditions to produce the corresponding carboxylic acid and alcohol. Under acidic conditions, the hydrolysis of ester groups will be accelerated, while under alkaline conditions, the hydrolysis reaction will be more thorough, resulting in carboxylate and methanol.
2. Reactive activity
1. Nucleophilic substitution
Amino group is a kind of nucleophilic star group which can induce nucleophilic substitution reaction with partial electroreagent. For example, when reacting with halogenated hydrocarbons, the nitrogen atoms of amino acids can attack the carbon atoms of halogenated hydrocarbons, thus forming new carbon-nitrogen bonds.
Nature and Specifications:
- Methyl 4-aminopyridine-2-carboxylate Chemical Properties
Melting point 129-130°
Boiling point 333.7±22.0 °C(Predicted)
density 1.238±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka 4.35±0.10(Predicted)
form powder to crystal
color White to Light yellow
| Item | Specification |
| Product Name | Methyl 4-aminopyridine-2-carboxylate |
| CAS No. | 71469-93-7 |
| Appearance | White to yellow-white powder |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Product Packaging
Product Usage:
(1) Medical care
1. drug synthesis intermediates
Methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 plays an important role in drug synthesis and is the core intermediate for the synthesis of many drugs. For example, it is used to synthesize drugs with antibacterial and antiviral activity. Due to its amino acids and further chemical variations in the Este group, other functional groups can be introduced to alter the activity and pharmacological properties of the drug. When synthesizing a specific antifungal drug, the reactive activity of the compound is to form drug molecules with a specific structure and activity and to be used for click compound condensation with other nitrogen-containing heterocyclic rings.
2. Research on nervous system drugs
Pyrazine compounds have specific potential for neurological drug research, and the methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 is no exception. It can be used as a tool compound to study neurotransmitter transmission and ion channel regulation. Some studies have suggested that the compound can have a regulatory effect on specific ion channels, such as potassium ion channels, thereby affecting the transmission of nerve impulses. This provides some theoretical basis and research direction for the development of new drugs for nervous system.
(2) Material science
1. Organic semiconductor materials
Due to the development of organic semiconductor materials, methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 is used in the preparation of organic semiconductor materials due to its unique molecular structure and electronic properties. The pyrazine ring and the amino ring can be involved in electron movement and transfer, and therefore can release substances with specific electrical and optoelectronic properties. By mixing or condensing this compound with other organic molecules, organic semiconductor films with different properties can be prepared for use in components such as organic light-emitting diodes (OLeds) and organic electromechanical effect transistors (OFETs).
2. Modification of polymer materials
In the field of polymer materials, methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 can be used as an auxiliary agent to improve the properties of polymer materials. For example, its introduction into epoxy resins can improve thermal stability and mechanical properties. This is because the amino group in the compound reacts with the epoxy group of the epoxy resin to form a cross-hemisphere structure, which improves the intermolecular force and the stability of the material.
(3) See the first volume of this book, On the Question of Agriculture, note (3).
1. Pesticide synthesis
In terms of insecticide synthesis, methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 can be used as an intermediate for the synthesis of insecticides with insecticide, sterilization and other activities. By modifying and changing its structure, pesticide varieties with different action mechanisms and objects can be developed. For example, reacting with compounds containing functional groups such as phosphorus and sulfur, organophosphorus or organosulfur pesticides with new structures can be synthesized, improving activity and selectivity.
2. Plant growth regulation device
Studies have shown that the compound can regulate the growth and development of plants to a certain extent. Affect plant hormone balance and metabolic processes, promote plant growth, flowering, fruit. For example, experiments have been carried out on some crops, and treatment with methyl 4-aminopyrazine-2-carboxylate CAS 71469-93-7 solution can improve crop yield and quality.
Related References:
Product Service:
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
6. Packing pictures and loading video before loading
7. Free Sample
8. Factory audit
Our Metrics
Our factory has advanced product production lines, and stable production capacity, which can achieve the goal of quickly providing high-quality products.
Our company is equipped with first-class equipment for the product production line to ensure the product quality to the greatest extent, to ensure that the net weight of the product is accurate, the packaging is well sealed, and it can meet the needs of long-distance transportation for export.
The Methyl 4-aminopyridine-2-carboxylate produced by our company has stable performance and a wide range of uses, which can meet the various needs of different customers.
The product price is competitive, and it has a good reputation and market share in countries all over the world.
If you need Methyl 4-aminopyridine-2-carboxylate or related products, please contact our company directly. Professional production and perfect service will definitely make you satisfied.
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
- After delivery, we will send a set of scanned copies of shipping documents to customers by mail, and mail the original documents in time. After the ship leaves the port, we update the shipping schedule to the customer every week and tell the customer when to arrive at the port. If customers encounter customs clearance problems, we will actively cooperate with customers to solve them. If it is an air or express delivery customer, we will provide the customer with the tracking number in time and update the information in time.
- After the customer receives the goods, we will promptly communicate with the customer about the quality and packaging of the product. Hope to get feedback from customers.
- We will provide customers with domestic market conditions and update prices in a timely manner. If conditions permit, we will also provide customers with the demand for the product in the country where they are located to help customers occupy the market.
- If there is any product quality problem, we will solve it in time. Compensation will also be made to the customer according to the third-party test report made by the customer. At present, the compensation rate due to quality objection is less than 1%.
- For our VIP customers, we have a very big preferential policy. If there is a quality problem with the product, we will be exempted from investigation and compensation, no more than three times a year.
- For ordinary customers, we will review the information provided by the customer, and then make compensation.
- Free samples can be provided before customers place an order.
- Customers can contact our technical staff at any time if they have any professional questions they do not understand. Technicians are online 24 hours a day.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
