Tert-butyldimethylsilyl Chloride CAS 18162-48-6
Directory Guidance on Tert-butyldimethylsilyl Chloride
Name: Tert-butyldimethylsilyl Chloride
Cas: 18162-48-6
Purity:Â 99%min
MOQ: 1KG
Basic Info:
| CAS No: | 18162-48-6 |
| Formula: | C6H15ClSi |
| EINECS: | 242-042-4 |
| Stock Availability | In stock |
| Brand Name | Zhishang chemical |
| Origin | China |
Chemical Structure
Product Introduction:
Tert-butyldimethylsilyl chloride (abbreviated as TBDMSCl, TBSCl) is an important sterically hindered organosilicon protective agent. In general, it is a white solid. The property of its molecule is the way it changes its shape when exposed to a specific chemical environment. This property can be made use of for many different functions and can be made use of in various applications.
Energetic hydrogens in natural substances can be changed by silyl teams under light response problems, resulting in intermediates with high chemical stability, and the sensitivity of other teams is not affected.
The effect of Tert-Butyldimethylsilyl chloride reacting with alcohol hydroxyl group to form silyl ether is particularly important. Compared with the common trimethyl chlorosilane protective agent, TBDMSCl silyl ether has higher stability.
Due to the steric hindrance of Tert-Butyldimethylsilyl chloride, it has excellent selectivity on polyhydroxyl substrates, and can easily selectively protect primary alcohols in the presence of secondary or tertiary alcohols.
Nature and Specifications:
- Density: 0.87 g/mL at 20 °C(lit.)
- Boiling point: 125 °C (lit.)
- Melting point: 86-89 °C
- Flash point: 73 °F
- Refractive index: n20/D 1.46
- Specific gravity: 1.225
| Item | Specification |
| Product Name | Tert-butyldimethylsilyl Chloride Powder |
| CAS No. | 18162-48-6 |
| Appearance | White-grey crystalline powder |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Product Packaging
Product Usage:
Tert-Butyldimethylsilyl chloride is widely used in the synthesis of drugs and natural products, such as the synthesis of prostaglandins, steroids, some antibiotics, hypolipidemic drugs loferstin and neoferstin auxiliary raw materials.
Tert-Butyldimethylsilyl chloride is a compound that has actually been used in the pharmaceutical sector for over 70 years. It is used to prepare other chemicals such as tert-butyl hydroquinone, tert-butylmethoxydibenzoylmethane, etc.
Silanizing agent. In organic synthesis, as hydroxyl protective agent, derivatization reagent is used for analysis and preparation. Tertiary alcohols can be protected. Reacts with alcohols to form silyl ethers. Determination of the conformation of cholesterol derivatives.
In addition, tert-butyldimethylsilyl chloride (TBDS) is a chemical used in the production of plastics, rubber and paints. It is also utilized in the printing market to make dyes as well as inks. In addition, it is used as a solvent for drying and cleaning chemicals, pharmaceuticals and food.
Related References:
- “Facile synthesis of all(6-O-tert-butyldimethylsilyl)-α-, β- and γ-cyclodextrins as protected intermediates” – NatureProtocols | 15 January 2021.
- “Application of tert-butyldimethylsilyl chloride/imidazole reagent in the identification of phospholipid molecular species by gas-liquid chromatography-mass spectrometry” – NIH, PubMed | 1979 Sep.
- Wikipedia
Product Service:
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
6. Packing pictures and loading video before loading
7. Free Sample
8. Factory audit
Our Metrics
Our factory has advanced product production lines, and stable production capacity, which can achieve the goal of quickly providing high-quality products.
Our company is equipped with first-class equipment for the product production line to ensure the product quality to the greatest extent, to ensure that the net weight of the product is accurate, the packaging is well sealed, and it can meet the needs of long-distance transportation for export.
The Tert-butyldimethylsilyl Chloride produced by our company has stable performance and a wide range of uses, which can meet the various needs of different customers.
The product price is competitive, and it has a good reputation and market share in countries all over the world.
If you need Tert-butyldimethylsilyl Chloride (TBDMCl) or related products, please contact our company directly. Professional production and perfect service will definitely make you satisfied.
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
- After delivery, we will send a set of scanned copies of shipping documents to customers by mail, and mail the original documents in time. After the ship leaves the port, we update the shipping schedule to the customer every week and tell the customer when to arrive at the port. If customers encounter customs clearance problems, we will actively cooperate with customers to solve them. If it is an air or express delivery customer, we will provide the customer with the tracking number in time and update the information in time.
- After the customer receives the goods, we will promptly communicate with the customer about the quality and packaging of the product. Hope to get feedback from customers.
- We will provide customers with domestic market conditions and update prices in a timely manner. If conditions permit, we will also provide customers with the demand for the product in the country where they are located to help customers occupy the market.
- If there is any product quality problem, we will solve it in time. Compensation will also be made to the customer according to the third-party test report made by the customer. At present, the compensation rate due to quality objection is less than 1%.
- For our VIP customers, we have a very big preferential policy. If there is a quality problem with the product, we will be exempted from investigation and compensation, no more than three times a year.
- For ordinary customers, we will review the information provided by the customer, and then make compensation.
- Free samples can be provided before customers place an order.
- Customers can contact our technical staff at any time if they have any professional questions they do not understand. Technicians are online 24 hours a day.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
