Tris Base CAS 77-86-1

Directory Guidance on Tris Base


Name: Tris Base Powder

Cas: 77-86-1

Purity: 99%min


Basic Info:

CAS No:77-86-1
Stock AvailabilityIn stock
Brand NameZhishang chemical

Chemical Structure

Tris Base

General Description:

Tris Base full name: Tris(hydroxymethyl)aminomethane, also known as tromethamine, Trometamol, typically described as Tris, is an organic substance with the molecular formula (HOCH2)3CNH2.

Tris Base is a sodium-free amino buffer base. It and its derivatives are commonly used in the preparation of buffers in biological experiments, making drugs, etc., especially in experiments related to proteins and nucleic acids.

Tris is used as a biological buffer .

Nature and Specifications:

Product Packaging


Product Usage:

Tris Base is an alkaline buffer that has a good buffering effect on metabolic acidosis and enzyme activity reactions. Therefore, it is often used in the preparation of buffers in biochemical and molecular biology experiments.

  • TAE and TBE buffers (used to dissolve nucleic acids) commonly used in biochemical experiments require Tris.
  • It can be used as pharmaceutical intermediates, biochemical reagents, pharmaceutical raw materials and acid-base balance regulators.
  • It is used for the barrier effect of organic preparations and clinical preparations, and can also be used for acute metabolic and respiratory acidemia.
  • It can absorb hydrogen ions to correct acidemia. It has a strong effect and can penetrate cell membranes. It is often used in acute metabolic and respiratory acidemia.
  • Tris Base buffer is also widely used as a solvent for nucleic acids, proteins, electrophoresis solvents, etc., and is used in large amounts. However, this buffer solution is not easy to store for a long time, the concentration of the original solution is low, and the number of times of use is also small.

Appearance Properties:

The product is generally white crystal or powder.

Soluble in ethanol and water, slightly soluble in ethyl acetate and benzene, insoluble in ether and carbon tetrachloride, destructive to copper and aluminum, and harmful to chemicals.

Related References:

  1. “Allergy to Moderna COVID-19 Vaccine Caused by Tromethamine” – JIACI | Excerpt: April 28, 2022.
  2. “Chemistry and Pharmacology of Tris Base” – Springer, Link | Excerpt: April 28, 2022.
  3. Wikipedia

Product Service:

1. Certificate Of Analysis (COA)

2. Material Safety Data Sheet (MSDS)

3. Route of synthesis (ROS)

4. Method of Aanlysis (MOA)

5. Nuclear Magnetic Resonance (NMR)

6. Packing pictures and loading video before loading

7. Free Sample

8. Factory audit

Buy Tris Base

As an experienced tris base manufacturer and supplier, Zhishang New Materials Co., Ltd. is committed to producing and selling high-quality products.

Our factory has advanced product production lines, and stable production capacity, which can achieve the goal of quickly providing high-quality products.

Our company is equipped with first-class equipment for the product production line to ensure the product quality to the greatest extent, to ensure that the net weight of the product is accurate, the packaging is well sealed, and it can meet the needs of long-distance transportation for export.

The Tris Base produced by our company has stable performance and a wide range of uses, which can meet the various needs of different customers.

The product price is competitive, and it has a good reputation and market share in countries all over the world.

If you need Tris Base Powder or related products, please contact our company directly. Professional production and perfect service will definitely make you satisfied.

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