Bulk Iguratimod Powder CAS 123663-49-0 | High Purity Chemical Intermediate

Bulk Iguratimod Powder CAS 123663-49-0 | High Purity Chemical Intermediate

CAS 123663-49-0 | Iguratimod

CAS No:123663-49-0
Formula:C17H14N2O6S
EINECS:808-127-0
Stock Availability:In stock
Brand Name:Zhishang New Materials
Origin:China
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Product Introduction of Iguratimod

Iguratimod (CAS: 123663-49-0), chemically designated as N-(3-formamido-4-oxo-6-phenoxy-4H-chromen-7-yl)methanesulfonamide, is a specialized synthetic methanesulfonamide derivative. In organic synthesis and analytical research, Iguratimod represents a highly structured chromone compound widely utilized as an active raw material and chemical standard in pharmaceutical development and advanced chemical formulation.
 
At Zhishang New Materials, we specialize in the custom synthesis and bulk supply of Iguratimod (CAS: 123663-49-0). Manufactured under controlled synthetic routes, our product consistently meets stringent purity thresholds, providing formulation scientists and procurement specialists with a dependable intermediate for ongoing research and industrial scaling.

Chemical Properties and Analytical Parameters

Accurate physical characterization is essential for analytical validation and quality control across batch processing operations.

  • Chemical Name: N-(3-formamido-4-oxo-6-phenoxy-4H-chromen-7-yl)methanesulfonamide

  • CAS Number: 123663-49-0

  • Molecular Formula: C17H14N2O6S

  • Molecular Weight: 374.37 g/mol

  • Physical Appearance: Off-white to light yellow powder

  • Assay Purity (HPLC): >= 98.0%

  • Melting Point: 238°C – 242°C

  • Loss on Drying: <= 0.5%

  • Heavy Metals: <= 10 ppm

  • Solubilization Profile: Soluble in dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF); sparingly soluble in methanol; practically insoluble in water.

Product Packaging

Bulk Iguratimod Powder CAS 123663-49-0 | High Purity Chemical Intermediate

Application of Iguratimod

Active Compound Synthesis & Derivatives
Serves as a fundamental core molecule for synthetic organic chemistry teams investigating novel chromone derivative libraries, structure-activity relationship (SAR) modeling, and sulfonyl-containing compound optimization.
 
Analytical Reference Standard
Utilized by analytical laboratories for chromatographic method validation, high-performance liquid chromatography (HPLC) calibration curves, and impurity profile comparison during raw material testing.
 
Process Scale-Up & Pilot Studies
Integrated into industrial pilot trials where consistent particle size distribution, crystal form stability, and predictable solubility behavior are required for scaling synthetic steps.
Our standard commercial grade maintains a minimum purity assay of 98.0% by HPLC. Custom analytical grades with higher purity thresholds can be prepared upon request for specific laboratory applications.

We accommodate evaluation orders starting from small laboratory quantities (10g, 100g, 1kg) up to multi-kilogram commercial pilot quantities.

Each shipment is accompanied by a batch-specific Certificate of Analysis (COA) verifying HPLC purity, melting range, loss on drying, heavy metals, and a complete Safety Data Sheet (SDS).

The powder is packaged in double-layer polyethylene bags, vacuum-sealed inside opaque light-protective aluminum foil bags, and housed within durable transport cartons or fiber drums.

Rigorous Quality Control and Analytical Verification

Our commitment to manufacturing consistency relies on advanced analytical verification protocols. Every production lot of Iguratimod (CAS: 123663-49-0) undergoes thorough testing prior to release:
 
Purity & Related Substances: High-Performance Liquid Chromatography with Photodiode Array Detection (HPLC-DAD) to verify purity and quantify related substances.
 
Chemical Structure Confirmation: Proton Nuclear Magnetic Resonance (1H-NMR) spectroscopy and Mass Spectrometry (MS) verification matching theoretical reference patterns.
 
Residual Solvent Profile: Gas Chromatography with Headspace sampling (GC-HS) ensuring compliance with solvent limit guidelines.
 
Elemental Analysis: Inductively Coupled Plasma Mass Spectrometry (ICP-MS) for heavy metal safety screening.

  • Standard Packaging: Available in 100 g, 1 kg aluminum foil vacuum bags, and 25 kg fiber drums with double inner polyethylene liners to prevent light oxidation and atmospheric moisture contamination.

  • Storage Conditions: Keep in tight, light-resistant containers. Store in a cool, dry, and well-ventilated area, preferably maintained between 2°C and 8°C for extended structural stability.

  • Safe Handling Practices: Iguratimod is an active organic intermediate intended for industrial and laboratory use only. Chemical operators must wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, protective eye goggles, and a dust mask, operating under adequate local exhaust ventilation.

Iguratimod (CAS: 123663-49-0) offered by Zhishang New Materials is distributed exclusively as a raw material and organic intermediate for research, development, synthesis, and industrial manufacturing applications.

It is not supplied for direct human or veterinary administration, direct consumer consumption, or home use. Formulators and industrial buyers are responsible for ensuring that their downstream applications and finished products comply with all relevant local and national regulatory standards.

  • Documentation Package Available: Certificate of Analysis (COA) per batch, Material Safety Data Sheet (MSDS / SDS), and Technical Data Sheet (TDS).

Manufacturer of Iguratimod

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Iguratimod Safety Information

WGK Germany WGK 3
HS Code 2935.90.9500
Storage Class11 – Combustible Solids

 

OrganicIntermediate

OrganicIntermediate is a professional foreign trade enterprise specializing in chemical raw materials. Upholding people-oriented values and cooperating with reliable manufacturers, we aim to become the world’s most trusted chemical supplier. Our production plant is located 50 meters south of the intersection of North Ring Road and 13th Road, Chenwang Street, Juancheng County, Heze City, Shandong Province. Our R&D laboratory is situated at R&D Base : F5, Yinfeng Biomedical City, Free Trade Zone, Jinan, Shandong. Integrating R&D and production, we strictly control product quality. With stable supply and sincere service, we welcome global customers for consultation and procurement.

Our Laboratory
Laboratory and Gas Chromatograph at Shandong Zhishang New Materials Co., Ltd.
Our Factory
The factory of Shandong Zhishang New Materials Co., Ltd.
Professional service
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This article was written by William, the chief chemist of Shandong Zhishang New Materials Co., Ltd.
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