Bulk Coenzyme Q10 Powder CAS 303-98-0 | High Purity Ubidecarenone Supplier
Product Introduction of Coenzyme Q10
Chemical Properties and Analytical Parameters
Precise chemical constants and physical properties are essential for technical directors and formulation engineers establishing manufacturing specifications.
Chemical Name: Ubidecarenone / 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
CAS Number: 303-98-0
Molecular Formula: C59H90O4
Molecular Weight: 863.34 g/mol
Appearance: Yellow to orange crystalline powder
Assay (Purity): 98.0% – 101.0% (HPLC on anhydrous basis)
Melting Point: 48°C – 52°C
Solubility: Practically insoluble in water; soluble in acetone, ether, and ethyl acetate; sparingly soluble in ethanol and vegetable oils.
Isomer Configuration: 100% All-Trans Isomer
Product Packaging
Application of Coenzyme Q10
Related Questions:
Q1: What is the difference between all-trans Coenzyme Q10 and synthetic isomer blends?
Q2: How do you prevent Coenzyme Q10 from recrystallizing in liquid or oil-based formulations?
To prevent recrystallization, formulators typically dissolve Coenzyme Q10 in lipid carriers (such as lipid oils or surfactants) at controlled temperatures between 45°C and 50°C, or utilize micro-encapsulation and self-emulsifying carrier systems (SEDDS).
Q3: Does your bulk Coenzyme Q10 meet global monograph standards?
Q4: What documentation is supplied with a commercial shipment?
Each shipment includes a lot-specific Certificate of Analysis (COA), Safety Data Sheet (SDS / MSDS), Non-GMO Statement, BSE/TSE-Free Certificate, and Allergen Declaration.
Molecular Structure and Fermentation Sou
Commercial Coenzyme Q10 can be synthesized chemically or produced via biological fermentation. Synthetic routes often produce cis-isomer impurities that may alter physical stability and functional performance.
Our manufacturing plant utilizes yeast fermentation (Rhodobacter sphaeroides strain optimization) followed by advanced crystallization cycles. This method delivers key operational benefits:
High Isomeric Purity: Guarantees the all-trans structure required for optimal stability in lipid matrices.
Contaminant Elimination: Avoids synthetic chemical residues and animal-derived pathogens, meeting strict global standards for clean-label formulations.
Consistent Particle Size: Standard mesh size options allow predictable flowability and uniform dispersion during encapsulation or emulsification.
Every production lot of Coenzyme Q10 (CAS: 303-98-0) undergoes comprehensive analytical verification in our ISO-certified QA laboratories prior to release:
Purity & Related Substances: High-Performance Liquid Chromatography (HPLC-UV) testing according to USP / EP monograph criteria.
Heavy Metal Analysis: Inductively Coupled Plasma Mass Spectrometry (ICP-MS) ensuring strict limits for lead, arsenic, cadmium, and mercury.
Residual Solvents: Gas Chromatography (GC-Headspace) checking for compliance with ICH Q3C guidelines.
Microbial Safety: Complete bioburden screening, including total aerobic microbial count (TAMC), yeast and mold limits, and absence of specified pathogens.
Regulatory Statement: Coenzyme Q10 supplied by Organic Intermediate is intended strictly for industrial manufacturing, laboratory research, and formulation processing. It is not intended for direct consumer diagnosis, medical treatment, or therapeutic disease mitigation. End-product manufacturers must ensure finished consumer items satisfy all relevant regional laws (such as FDA, EFSA, or local cosmetics and dietary supplement rules).
Standard Packaging: Packed in light-proof, vacuum-sealed aluminum foil bags of 1 kg, 5 kg, or 25 kg fiber drums with double PE inner liners.
Storage Protocol: Store in a dry, cool environment (below 25°C), shielded from light and air exposure. Unopened original packaging provides a shelf life of 24 months.
Manufacturer of Coenzyme Q10
API, usually referring to chemical raw materials, is the active ingredient in chemical drug formulations.
Coenzyme Q10 Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-26 |
| WGK Germany | 3 |
| RTECS | DK3900000 |
| F | 8-10 |
| TSCA | TSCA listed |
| HS Code | 29146990 |
| Storage Class | 11 – Combustible Solids |
OrganicIntermediate is a professional foreign trade enterprise specializing in chemical raw materials. Upholding people-oriented values and cooperating with reliable manufacturers, we aim to become the world’s most trusted chemical supplier. Our production plant is located 50 meters south of the intersection of North Ring Road and 13th Road, Chenwang Street, Juancheng County, Heze City, Shandong Province. Our R&D laboratory is situated at R&D Base : F5, Yinfeng Biomedical City, Free Trade Zone, Jinan, Shandong. Integrating R&D and production, we strictly control product quality. With stable supply and sincere service, we welcome global customers for consultation and procurement.
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This article was written by William, the chief chemist of Shandong Zhishang New Materials Co., Ltd.
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