Sodium Tert-butoxide CAS 865-48-5
Name: Sodium Tert-butoxide
Cas: 865-48-5
Purity:Â 99%min
MOQ: 1KG
Basic Info:
| CAS No: | 865-48-5 |
| Formula: | C4H9NaO |
| EINECS: | 212-741-9 |
| Stock Availability | In stock |
| Brand Name | Zhishang chemical |
| Origin | China |
Chemical Structure
Product Introduction:
Sodium tert-butoxide, also known as sodium tertiary butoxide, Sodiumtert-butoxide. Water-soluble white crystalline powder, molecular formula is C4H9NaO, molecular weight is 96.10.
Sodiumtert-butoxide is stable under normal temperature and pressure and is slightly harmful to water. Avoid contact of undiluted or large quantities of product with groundwater, water courses or sewage systems during use. Its powder products are mainly used as organic synthesis intermediates and pharmaceutical intermediates.
Sodium tertiary butoxide is a strong base with weak nucleophilicity, similar to potassium tertiary butoxide in chemical reaction. Its products react with water and dissolve in water, ethanol, methanol, etc.
Sodium tert-butoxide is used to treat various diseases. is a drug specially developed to treat cancer, and it is also an ingredient in many medicines.
Nature and Specifications:
- Density: 1,104 g/cm3
- Melting point: 180 °C
- Boiling point: 180°C/1mmHg
- Refractive index: n20/D1.413
- Flash point: 12°C
- Water solubility: reacts
| Item | Specification |
| Product Name | Sodium tert-butoxide Powder |
| CAS No. | 865-48-5 |
| Appearance | White or off-white powder |
| Shelf Life | 2 years |
| Packing | 1kg/bag,25kg/bag or as your requirements |
Product Packaging
Product Usage:
Sodium tert-butoxide is mainly used as organic synthesis intermediate and pharmaceutical intermediate. Or as a strong base, it is widely used in reactions such as condensation, rearrangement and ring opening in chemical industry, medicine, pesticide and organic synthesis. Therefore, sodium tert-butoxide is increasingly favored by fine chemicals, pesticides and pharmaceutical industries.
Medical use:
Sodium tert-butoxide can be used as a safe and effective sodium hydride substitute for the coupling of hydroxyethyladenine and diethyl p-toluenesulfonyloxymethylphosphonate to 9-[2-(diethyl Phosphorylmethoxy)ethane]adenine (diethyl-PMEA), which is an important intermediate in the preparation of adefovir dipivoxil.
Sodium tert-butoxide is a drug that has been used in cancer treatment for many years. It was developed to treat and prevent metastases from extremely difficult-to-treat and often fatal prostate cancer. However, recent advances in the field of anticancer medicine have enabled the development of many new drugs.
It is an effective and safe drug for bladder cancer. It has been used for bladder cancer patients since its inception. As a prescription drug, it can be given to bladder cancer patients who have not responded to other treatments.
Administration of Sodium tertiary butoxide cured about 80% of patients with advanced or poorly differentiated bladder cancer and prevented tumor recurrence in about half of patients. The US FDA approved the product in March 2010 after a two-year review period.
Sodium tert-butoxide is the sodium salt of butyl tert-butanol. It is the first drug developed specifically to treat cancer. In addition to the above-mentioned effects, it has superior chemotherapeutic activity against colon cancer, lung cancer and skin cancer.
Other apps:
Sodium tert-butoxide was used as a promoter to promote the synthesis of biaryl groups by C-H bond arylation between aromatic compounds and halogenated aromatic hydrocarbons. Involved in the desulfonylation of N-indole and N-azaindole.
Sodium tertiary butoxide is used as a base to synthesize aryl tertiary butyl ethers from unactivated aryl halides in the presence of a palladium catalyst. It is the base in the palladium-catalyzed amination reaction. Also used for olefin and CO2 synthesis of sodium acrylate.
In the presence of 10-phenanthroline derivatives, auxiliary halogenated aromatic hydrocarbons are coupled with benzene derivatives. The first subgroup transition metal precatalyst can be activated.
Related References:
- “‘Conjugated’ Substitution of Hydrogens in Pentabromotoluene Methyl” – Springer, Link | August 2005.
- “Synthesis of Novel N-arylpyrimidin-2-amine Derivatives Using Palladium Catalysts” – PubMed, NIH | 2008 Apr 9.
- Wikipedia
Product Service:
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
6. Packing pictures and loading video before loading
7. Free Sample
8. Factory audit
Our Metrics
Our factory has advanced product production lines, and stable production capacity, which can achieve the goal of quickly providing high-quality products.
Our company is equipped with first-class equipment for the product production line to ensure the product quality to the greatest extent, to ensure that the net weight of the product is accurate, the packaging is well sealed, and it can meet the needs of long-distance transportation for export.
The sodium tert-butoxide produced by our company has stable performance and a wide range of uses, which can meet the various needs of different customers.
The product price is competitive, and it has a good reputation and market share in countries all over the world.
If you need sodium tertiary butoxide or related products, please contact our company directly. Professional production and perfect service will definitely make you satisfied.
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
- After delivery, we will send a set of scanned copies of shipping documents to customers by mail, and mail the original documents in time. After the ship leaves the port, we update the shipping schedule to the customer every week and tell the customer when to arrive at the port. If customers encounter customs clearance problems, we will actively cooperate with customers to solve them. If it is an air or express delivery customer, we will provide the customer with the tracking number in time and update the information in time.
- After the customer receives the goods, we will promptly communicate with the customer about the quality and packaging of the product. Hope to get feedback from customers.
- We will provide customers with domestic market conditions and update prices in a timely manner. If conditions permit, we will also provide customers with the demand for the product in the country where they are located to help customers occupy the market.
- If there is any product quality problem, we will solve it in time. Compensation will also be made to the customer according to the third-party test report made by the customer. At present, the compensation rate due to quality objection is less than 1%.
- For our VIP customers, we have a very big preferential policy. If there is a quality problem with the product, we will be exempted from investigation and compensation, no more than three times a year.
- For ordinary customers, we will review the information provided by the customer, and then make compensation.
- Free samples can be provided before customers place an order.
- Customers can contact our technical staff at any time if they have any professional questions they do not understand. Technicians are online 24 hours a day.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
