CAS 604-69-3 | β-D-Glucose Pentaacetate: A Manufacturer’s Guide to High-Purity Sugar Chemistry Intermediates and Industrial Value

Directory Guidance on Beta-D-Glucose Pentaacetate

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Name: Beta-D-Glucose Pentaacetate

Cas: 604-69-3

Purity: 99%min

MOQ: 1KG

Core Specifications and Factory Benchmarks of CAS 604-69-3

Operating our own synthesis facility allows us to implement precise crystallization and temperature controls to ensure every batch leaving our warehouse meets or exceeds the following laboratory and industrial-grade standards:
  • Chemical Formula: C₁₆H₂₂O₁₁
  • Molecular Weight: 390.34
  • Appearance: Highly crystalline white to off-white crystalline powder
  • GC Purity: ≥ 98.0% / ≥ 99.0% (Customizable to premium pharmaceutical grade)
  • Melting Point Range: 130 – 132 °C
  • Loss on Drying (Moisture): ≤ 0.5% (The product is slightly hygroscopic; shipped in fully sealed, moisture-proof packaging)

Chemical Structure

Beta-D-Glucose Pentaacetate

Basic Information of Beta-D-Glucose Pentaacetate:

In the fields of modern biopharmaceutical research, polysaccharide and oligosaccharide synthesis, and premium food additives, β-D-Glucose Pentaacetate (also known as 1,2,3,4,6-Penta-O-acetyl-β-D-glucopyranose, CAS No.: 604-69-3) plays an irreplaceable role as a classic fully protected carbohydrate building block. As a direct, source-level manufacturer specializing in carbohydrate chemistry and pharmaceutical intermediates for years, we understand that downstream R&D institutions and industrial clients demand strict standards for product purity, specific optical rotation, and α/β anomer ratios during glycosylation scale-up.

Manufacturing Technical Edge and Quality Control

Conventional carbohydrate acetylation processes easily generate unpredictable α/β anomeric mixtures. Because their physical properties are highly similar, subsequent separation is difficult and costly. We have implemented several proprietary process optimizations in our large-scale production line:
  1. Stereospecific Condensation Control: By using specialized weak base or Lewis acid catalytic systems, we strictly regulate reaction kinetics and temperatures. This pushes the equilibrium heavily toward the thermodynamically more stable β-configuration, minimizing α-anomer formation at the source.
  2. Multi-Stage Recrystallization: We utilize a proprietary composite solvent recrystallization technique. This completely removes residual acetic acid and acetic anhydride from the reaction (reducing free acids to absolute minimums) while ensuring uniform crystal size. This drastically enhances the chemical stability and shelf life of the product in open air.
  3. Trace and Heavy Metal Mitigation: As a critical pharmaceutical intermediate, our plant strictly manages manufacturing equipment metallurgy and pipeline rinsing protocols. We restrict heavy metals like iron, lead, and arsenic to ultra-low ppm levels, meeting direct warehouse-in inspection standards for downstream pharma giants.

Product Usage:

The unique fully protected structure of β-D-Glucose Pentaacetate offers exceptional flexibility in synthesizing carbohydrate-containing molecules:
  • Glycosyl Donors and Oligosaccharide Synthesis: Under Lewis acid catalysis, the anomeric acetoxy group (1-O-acetyl) acts as an excellent leaving group for synthesizing various simple or complex glycosides, oligosaccharides, and glycoconjugates. It can also be easily converted into highly reactive glycosyl halides (like acetobromo-alpha-D-glucose) or thioglycosides.
  • Prodrug and Pharmaceutical Development: Research shows that specific carbohydrate-protected derivatives exhibit unique biological activities in regulating or stimulating insulin release from rat islet cells. It also serves as a vital precursor for introducing sugar moieties into various antiviral and antitumor complexes.
  • Specialty Additives and Fragrance Precursors: In fine chemicals, premium daily cosmetics, and the food industry, it is widely utilized as a heat-resistant, stable flavor precursor or specialty functional additive.

Related References:

Why Partner with Us as Your Bulk Supplier?

By sourcing β-D-Glucose Pentaacetate (CAS: 604-69-3) directly from our manufacturing facility, you bypass trading margins, gaining competitive factory-direct pricing and a resilient supply chain.
  • Stock and Scale: We maintain ton-scale inventories to support rapid delivery from kilogram-scale pilot samples to multi-ton commercial volumes.
  • Complete Technical Dossier: Every shipment is accompanied by H-NMR charts, GC purity chromatograms, specific optical rotation sheets, and up-to-date GHS-compliant SDS.
  • Compliant Hazardous/Safe Logistics: Packaged in standard 1kg aluminum foil bags or 25kg fiber drums, strictly supporting compliant international sea and air freight logistics.

To help us optimize your procurement costs and accelerate your project timeline, please let us know:
  • Your expected initial sample size / annual demand
  • Any specific requirements for the α/β ratio or target purity
  • Your destination port or delivery location
We will immediately assign a senior carbohydrate chemical engineer and dedicated account manager to provide 1-on-1 technical consultation and a direct factory quotation

Packaging and Shipping

Small Packaging (Sample List)

100g/bottle 500g/bottle 1kg/bottleHDPE Plastic Bottle Fluoroplastic Bottle
Aluminum Foil Bag Vacuum Packaging

Medium Packaging

5kg/drum 10kg/drum Double-Layer PE Bag
Outer Aluminum Foil Bag Cardboard Drum Packaging

Large Packaging

25kg Cardboard Drum

Packaging Structure:

Inner Layer: Double-Layer PE Bag
Middle Layer: Aluminum Foil Bag (Optional)
Outer Layer: 25kg Cardboard Drum

Contact us for the latest quotation and free samples of Beta-D-Glucose Pentaacetate Powder

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