Bulk Dihydromyricetin Powder CAS 27200-12-0 | >98% HPLC Supplier

Bulk Dihydromyricetin Powder CAS 27200-12-0 | >98% HPLC Supplier

CAS 27200-12-0 | Dihydromyricetin

CAS No:27200-12-0
Formula:C15H12O8
EINECS:200-001-8
Stock Availability:In stock
Brand Name:Zhishang New Materials
Origin:China
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Product Introduction of Dihydromyricetin

Dihydromyricetin (CAS: 27200-12-0), also known as Ampelopsin or DHM, is a bioflavonoid belonging to the flavanonol class of polyphenolic compounds. Naturally concentrated in the stems and leaves of Ampelopsis grossedentata (commonly known as Vine Tea or Teng Cha), Dihydromyricetin features a unique hydroxylated chroman-4-one skeleton that confers exceptional radical scavenging capacity and structural versatility in organic synthesis.
 
At Zhishang New Materials, we produce and supply high-purity Dihydromyricetin derived from sustainably harvested botanical sources. Our standardized extraction and crystallization processes yield consistent batch-to-batch quality with purity levels reaching up to 98.0% by HPLC, making it an ideal functional raw material for dietary supplement formulation, cosmetic active blends, and advanced chemical research.

Chemical Identification and Physical Properties

Providing accurate physicochemical constants allows formulation scientists and analytical chemists to optimize solubility, compatibility, and shelf-life stability in finished compound matrices.

  • Chemical Name: (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one

  • CAS Number: 27200-12-0

  • Molecular Formula: C15H12O8

  • Molecular Weight: 320.25 g/mol

  • Botanical Source: Ampelopsis grossedentata (Teng Cha)

  • Appearance: Off-white to light coarse crystalline powder

  • Assay (Purity): >= 98.0% (High-Performance Liquid Chromatography – HPLC)

  • Melting Point: 245°C – 250°C

  • Solubility: Soluble in hot water, ethanol, and acetone; sparingly soluble in cold water; insoluble in chloroform and petroleum ether.

Product Packaging

Bulk Dihydromyricetin Powder CAS 27200-12-0 | >98% HPLC Supplier

Application of Dihydromyricetin

Dietary Supplement Manufacturing & Nutraceutical Formulations
Dihydromyricetin is widely utilized as a key active ingredient in modern dietary formulations focusing on antioxidant defense, metabolic support, and cell protection models. Its high polyphenolic content makes it an effective compound for capsule encapsulation, tablet compression, and functional beverage pre-mixes.
 
Cosmetic & Topical Formulations
In skin-care chemistry, Dihydromyricetin is incorporated into topical creams, serums, and anti-aging matrices due to its natural antioxidant capacity and ability to neutralize reactive oxygen species (ROS). It aids in stabilizing emulsion systems while serving as a functional skin-conditioning agent.
 
Organic Synthesis and Research Intermediate
As a heavily hydroxylated flavanonol core structure, Dihydromyricetin serves as a valuable precursor in organic chemistry research for synthesizing novel flavonoid derivatives, metal-ion complexes, and targeted biochemical probes.
We utilize an eco-friendly food-grade water and ethanol extraction process. No chlorinated solvents or harsh petrochemical extraction media are used, ensuring compliance with strict international residual solvent limits.
When stored in its original unopened packaging under cool, dry conditions away from light, Dihydromyricetin maintains a shelf life of 24 months from the manufacturing date.
 
While our standard stock grade is >= 98.0% HPLC purity, we can accommodate custom orders for 50%, 80%, or 90% technical grades based on your specific formulation or budget requirements.

Every shipment includes a lot-specific Certificate of Analysis (COA), Safety Data Sheet (SDS / MSDS), Technical Data Sheet (TDS), and statements confirming BSE/TSE-Free, Non-GMO, and Allergen status.

Quality Control, Analytical Standards & EEAT Compliance

Our state-of-the-art manufacturing infrastructure operates under stringent ISO 9001 and GMP-compliant processing parameters. From raw plant selection to final vacuum drying, every step is strictly monitored to eliminate contaminants and preserve active flavonoid integrity.

Our analytical testing suite includes:

  • Assay & Purity Verification: High-Performance Liquid Chromatography (HPLC-DAD) against certified reference standards.

  • Structural Confirmation: Fourier-Transform Infrared Spectroscopy (FTIR) and Nuclear Magnetic Resonance (NMR) spectral matching.

  • Heavy Metal Limits: Inductively Coupled Plasma Mass Spectrometry (ICP-MS) testing ensuring Lead <= 1.0 ppm, Arsenic <= 1.0 ppm, Cadmium <= 0.5 ppm, and Mercury <= 0.1 ppm.

  • Solvent Residue Limits: Gas Chromatography with Headspace (GC-HS) verifying full compliance with ICH Q3C guidelines for residual extraction solvents (Ethanol/Water processing).

  • Microbiological Safety: Comprehensive screening for Total Aerobic Microbial Count (TAMC), Yeast/Mold, Salmonella, and E. coli.

  • Thermal Sensitivity: Dihydromyricetin exhibits stability under standard processing conditions but should avoid prolonged exposure to temperatures exceeding 80°C in aqueous media to prevent phenolic oxidation.

  • pH Stability: Demonstrates optimal stability in neutral to slightly acidic aqueous environments (pH 3.5 – 6.5). Highly alkaline environments may induce oxidation or structural degradation.

  • Recommended Packaging: Packed in light-blocking, vacuum-sealed double PE food-grade inner bags enclosed within aluminum foil moisture-barrier bags and high-density fiber drums (1 kg, 5 kg, 10 kg, and 25 kg configurations).

  • Storage Conditions: Keep tightly sealed in a cool, dry, dark environment away from direct sunlight, ambient heat, and strong oxidizing agents. Recommended storage temperature: 2°C – 20°C.

Dihydromyricetin (CAS: 27200-12-0) supplied by Organic Intermediate is distributed exclusively as a raw material intended for industrial manufacturing, laboratory research, dietary supplement production, and cosmetic formulation.

It is not intended for direct human consumption as a finished product, nor for the diagnosis, treatment, mitigation, or prevention of any disease or medical condition. Finished product formulators are solely responsible for verifying compliance with national regulatory frameworks (including US FDA NDI/GRAS status, EU Novel Food regulations, and local cosmetic safety standards).

Manufacturer of Dihydromyricetin

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Dihydromyricetin Safety Information

Safety Statements 24/25
WGK Germany 3
HS Code 29329990
Storage Class11 – Combustible Solids

 

OrganicIntermediate

OrganicIntermediate is a professional foreign trade enterprise specializing in chemical raw materials. Upholding people-oriented values and cooperating with reliable manufacturers, we aim to become the world’s most trusted chemical supplier. Our production plant is located 50 meters south of the intersection of North Ring Road and 13th Road, Chenwang Street, Juancheng County, Heze City, Shandong Province. Our R&D laboratory is situated at R&D Base : F5, Yinfeng Biomedical City, Free Trade Zone, Jinan, Shandong. Integrating R&D and production, we strictly control product quality. With stable supply and sincere service, we welcome global customers for consultation and procurement.

Our Laboratory
Laboratory and Gas Chromatograph at Shandong Zhishang New Materials Co., Ltd.
Our Factory
The factory of Shandong Zhishang New Materials Co., Ltd.
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This article was written by William, the chief chemist of Shandong Zhishang New Materials Co., Ltd.
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